Pharmadry®真空桨叶干燥机

信息来源: | 发布日期: 2013-02-04 | 浏览量:
关键词:真空桨叶干燥机,真空干燥机,桨叶干燥机

Pharmadry®真空桨叶干燥机,干燥时间短,非常适合干燥的自由流动,敏感的药物成分和精细化学品。专为满足严格的cGMP和FDA的指导原则

搅拌器在后方的支持,与外部交换的机械密封。专为频繁的产品变化。优异的清洁能力,使用CIP系统,简单的验证。

良好的产品放电特性与产品的残余物可忽略不计,适当缩小壁的间隙,最小的血管深度和特殊的搅拌器叶片设计的搅拌器。
惰性气体

湿滤饼或淤浆输送到干燥器中之前与氮的含氧气氛中通过控制位移惰化容器内部。此过程可以防止可能形成在容器内的爆炸性气体环境。

填充

惰性化后完成从一个离心机或吸滤器,或依赖于应用程序浆料送入干燥器的湿滤饼。
烘干

为了有效地进行干燥,干燥机通常是抽真空的步骤和在相同的时间加热。在干燥过程中,产品的搅拌。的干衣机的产品被保持在真空下,在最大允许温度,直到达到所需的最终产品的湿度水平。
冷却

干燥完成后的产品被冷却下来之前排出。

出料

将干燥和冷却后的产物被排出直通侧排出阀。该产品被输送到排出阀由搅拌器。
清洁的

使用喷球所有产品的清洁液被喷洒到湿的内表面中的设备之间的单个批次或产品变更超过内部清洁。这提供了全面有效地清洁机内部。

The Pharmadry® vacuum paddle dryer with short drying times is well suited for the drying of freely flowing, sensitive pharmaceutical ingredients and fine chemicals. Designed to meet stringent cGMP and FDA guidelines

Agitator supported at the rear, with externally exchangeable mechanical seal. Designed for frequent product changes. Excellent cleanability using CIP Systems, simple validation.

Good product discharge characteristics with negligible product residues, due to narrow agitator to wall clearances, minimal vessel depth and a special agitator blade design.
Inerting

Prior to feeding wet cake or slurry into the dryer the vessel interior is inerted by a controlled displacement of the oxygen containing atmosphere with Nitrogen. This procedure prevents the potential formation of an explosive atmosphere in the vessel interior.

Filling

After inertization is completed wet filter cake from a centrifuge or Nutsche filter, or dependent upon the application slurry is fed into the dryer.
Drying

For efficient drying the dryer is typically evacuated in steps and heated up at the same time. During the drying process the product is agitated. The dryer is maintained under vacuum and at the maximum allowable temperature for the product until the final required product humidity level is reached.
Cooling

After drying is completed the product is cooled down prior to discharging.

Discharging

The dried and cooled product is discharged thru the side discharge valve. The product is transported to the discharge valve by the agitator.
Cleaning

Using spray balls a cleaning fluid is sprayed onto all product wetted internal surfaces for the internal cleaning of the equipment in between individual batches or for product change over. This provides for full and efficient cleaning of the dryer interior.

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